The Ryder Lab





Now seeking post-docs and graduate students to perform NIH-funded research on C. elegans maternal RNA regulation and RNA-binding proteins. Please contact Sean directly at the email address listed below.

We are interested in understanding the mechanisms that govern post-transcriptional regulation of gene expression during development and complex disease. Our research is focused primarily in three areas:

1. Post-transcriptional regulatory mechanisms involved in axis polarization and cell fate specification during Caenorhabditis elegans embryogenesis.

2. Characterization of post-transcriptional regulatory mechanisms that guide oligodendrocyte differentiation and myelin formation in the vertebrate central nervous system.

3. Identification of small molecule inhibitors of RNA-binding protein function using high throughput screening approaches.

We employ a combination of biochemical and molecular genetic methods, bioinformatics, chemical biology, biophysics, and structural analyses in our studies, with a focus on quantitative measurements.

Read more about our research here.

Sean P. Ryder, Ph.D.
Associate Professor
Department of Biochemistry and Molecular Pharmacology
University of Massachusetts Medical School

Contact Information:

Sean P Ryder, Ph.D.
Department of Biochemistry and Molecular Pharmacology
University of Massachusetts Medical School

364 Plantation Street, LRB-906
Worcester, MA 01605

Office Phone: 508-856-1372
Lab Phone1: 508-856-3568
Lab Phone2: 508-856-3718
General Fax: 508-856-6464

E-mail: Send an email

Campus Address: Lazare Research Building, 9th floor, Office 906

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Our laboratory is located on the 9th floor of the Lazare Research Building in the Department of Biochemistry and Molecular Pharmacology at the University of Massachusetts Medical School. We enjoy a collaborative research environment that includes colleagues with related interests in worm biology, RNA biochemistry, developmental biology, or biophysics.

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