Binding Site Database
The Wolfe Lab
is currently an Assistant Professor at UMass Medical School in the Program in Gene Function & Expression and the Department of Biochemistry & Molecular Pharacology.
Our esteemed staff includes:
Developer of an omega-based bacterial one-hybrid system for performing binding site selections.
Focused on creating a broad catalog of specificities for zinc finger proteins and using these to create ZFNs for use in Zebrafish.
Developing new and improved ZFNs for use in Zebrafish.
Dr. Joseph McNulty:
Developing ZFN methods for targeted engineering of the Zebrafish genome.
Optimizing ZFN methods for targeted gene knockouts in Zebrafish.
Characterizing and Engineering ZFP specificities.
Former Lab Members
Dr. Xiangdong Meng:
Developer of the original bacterial one-hybrid system and pioneer of ZFNs in Zebrafish. (Now at Sangamo BioSciences)
| ©2008 Wolfe Lab