Our research is focused on three related areas:

• Understanding fundamental aspects of protein-DNA recognition - recent focus on homeodomain-DNA recognition
• Engineering artificial transcription factors for gene regulation/modification - recent focus on targeted gene knockouts in the zebrafish
• Developing new selection technologies to facilitate the first two goals

This web site contains information about our current research interests as well as links to published protocols and datasets.

Questions about or problems with this website should be addressed to scot.wolfe@umassmed.edu